Research Roundup

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Debbie Rigby rounds up the latest in research news

Current treatment options for postmenopausal vaginal atrophy

Vulvovaginal atrophy (VVA) affects up to 50%–60% of postmenopausal women, with symptoms of dryness, burning, itching, vaginal discomfort, pain and burning when urinating, dyspareunia, and spotting during intercourse. Treatment options include systemic and topical hormone replacement therapy, the use of selective estrogen receptor modulators, vaginal dehydroepiandrosterone, use of lubricants and moisturizers, as well as non-drug therapies.

International Journal of Women’s Health 2018:10 387–395.

Chocolate consumption and risk of cardiovascular diseases

A meta-analysis of 23 prospective studies has concluded that chocolate consumption may be associated with reduced risk of CVD at <100 g/week consumption. The most appropriate dose of chocolate consumption for reducing risk of CVD was 45 g/week (RR 0.890). Higher levels may negate the health benefits and induce adverse effects associated with high sugar consumption.

Heart Published Online First: 30 July 2018.

Infantile colic

Infantile colic is a common, self-resolving condition. The probiotic Lactobacillus reuteri DSM17938 may be trialled for exclusively breastfed infants with colic. Its efficacy in formula-fed babies is unknown. Hydrolysed formula and hypoallergenic diet in breastfeeding mothers is possibly effective. An allergy to cow’s milk protein accounts for a minority of cases. Simethicone, proton pump inhibitors, spinal manipulation, lactase and soy formula are ineffective.

Aust Prescr 2018;41:105-10.

Australian clinical guidelines for the diagnosis and management of atrial fibrillation 2018

Executive summary of new guidelines developed by the National Heart Foundation of Australia (NHFA) and the Cardiac Society of Australia and New Zealand (CSANZ). The importance of deciding between a rate and rhythm control strategy at the time of diagnosis and periodically thereafter is highlighted. The CHA2DS2-VA score — the sexless CHA2DS2-VASc score — is recommended for predicting stroke risk in AF.

Med J Aust 2018 doi: 10.5694/mja18.00646



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