Debbie Rigby takes a look at the latest in research news
Up to 92% of patients demonstrate at least one critical error when using an inhaler, which can lead to decreased effectiveness of the inhaled drug. in this study conducted in community pharmacies, possession of more than one inhaler, use of rescue inhaler, and poor control of asthma were found to be significant predictors of having at least one critical error.
In this Canadian retrospective population-based cohort study including over 1 million patients, almost one out of two community-dwelling older adults (48.3%) use a potentially inappropriate medicine (PIM) according to the 2015 Beers criteria. The most prevalent PIMs were benzodiazepines (25.7%), proton-pump inhibitors (21.3%), antipsychotics (5.6%), antidepressants (5.0%) and long-duration sulfonylureas (3.3%).
Family Practice 2020:173-9.
Post-hoc analyses of four RCTs in adults with asthma shows that once-daily tiotropium Respimat add-on to ICS or ICS/LABA therapy was effective and well tolerated in patients with asthma independent of age. The analyses clearly show that the bronchodilator effects of antimuscarinic therapy with tiotropium are similar in younger and older patients. Previous studies have shown a reduced bronchodilator response in older people.
Journal of Allergy and Clinical Immunology: In Practice (2020)
In this RCT of 253 adults, a commercially available zinc acetate lozenge (containing 13 mg elemental zinc) was not effective in treating the common cold when instructed to be used for 5 days after the first symptoms. Taste has been a common problem in previous zinc lozenge trials, but a third of zinc participants did not complain of any adverse effects.
BMJ Open 2020;10:e031662.