Research Roundup

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Debbie Rigby’s roundup of the latest news in the research world

Zinc acetate lozenges for treating the common cold

A meta-analysis of randomised controlled trials has concluded that zinc acetate lozenges reduce the duration of the common cold by nearly three days. This estimate is compared with the 7 day average duration of colds. This effect is considered clinically relevant and appears widely applicable. Elemental zinc dose varied between 80 and 92 mg/day in the three studies included in the meta-analysis.

British Journal of Clinical Pharmacology 2016.


Drugs That May Cause or Exacerbate Heart Failure

This scientific statement is designed to serve as a comprehensive and accessible source of drugs that may cause or exacerbate heart failure to assist healthcare providers in improving the quality of care for these patients. Common OTC and CM medicines that can cause or exacerbate include NSAIDs, cough and cold products that contain vasoconstrictors such as phenylephrine, anti-acid products with high sodium content, ginseng, ephedra-like products, vitamin E supplements, aconite, gossypol and liquorice.

Circulation. 2016;134:00–00.


The impact of pharmacist-managed clinic on medication adherence and health-related quality of life in patients with COPD

A prospective randomized controlled study of 244 patients with COPD has demonstrated improvement of medication adherence and the health-related quality of life in patients with COPD with a pharmacist-managed clinic. A significant reduction in exacerbation rate, hospitalization rate, and smoking behavior was observed.

Patient Preference and Adherence 2016:10 1197–1203


Is coffee consumption associated with a lower risk of hyperuricaemia or gout?

A systematic review and meta-analysis has concluded there is insufficient evidence to validate the association between coffee consumption and a lower risk of hyperuricaemia. However, coffee consumption may be associated with a lower risk of incident gout.

BMJ Open 2016;6:e009809.


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