Research Roundup

Debbie Rigby rounds up the latest in research news  

Association Between Beliefs and Adherence to Inhaled Controller Medication Among Older Adults with Asthma

In this questionnaire with older patients (aged 60 years and older) less than half had good adherence to inhaled corticosteroids (ICS). Patients’ concerns and beliefs about the necessity of their asthma preventer were significantly associated with adherence. Those who perceived asthma as an illness with a longer timeline were more likely to be adherent to ICS. The stronger the belief in the necessity of ICS, the better the adherence.

Patient Preference and Adherence 2020:14 1351–1359.


Considerations for optimal prescribing in older adults

This case-based article demonstrates an approach to assessing select medications commonly taken by older adults. While potential concerns for each medication are described, individualization of approach, clinical judgment, and special consideration for principles of geriatric care remain foundational when prescribing and assessing medication regimens in older adults.

Canadian Family Physician August 2020;66(8):584-587.


Frailty in Chronic Obstructive Pulmonary Disease and Risk of Exacerbations and Hospitalizations

Frailty is common in chronic obstructive pulmonary disease (COPD) and is associated with an increased risk of non-COPD hospitalisations. Among the individual frailty components, low handgrip strength was associated with increased risk of COPD exacerbations over a 2-year period. Measuring handgrip strength may identify COPD patients who could benefit from programs to reduce COPD exacerbations.

International Journal of Chronic Obstructive Pulmonary Disease 2020;15:1967-76.


Major GI bleeding in older persons using aspirin: incidence and risk factors in the ASPREE randomised controlled trial

Data from the ASPREE trial which explored the place of aspirin in primary prevention in persons 70 years and older, shows a 60% increased risk of major GI bleeding compared to placebo. The absolute 5-year risk of bleeding was 0.25% for a 70 year old not on aspirin and up to 5.03% for an 80 year old taking aspirin with additional risk factors. Risk factors increasing the risk of bleeding included advancing age, smoking, hypertension, higher waist circumference and CKD. 

Gut 2020;0:1–8.


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