Research Roundup

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Debbie Rigby rounds up the latest in research news

Management of Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) is a chronic, often debilitating, and highly prevalent disorder of gut-brain interaction. This US clinical guideline describes information on diagnosis, treatment, and duration of therapy. Soluble fibre (not insoluble fibre), peppermint and TCAs can be used to treat global IBS symptoms. Probiotics, faecal transplant, and polyethylene glycol (PEG) products are not recommended.

American Journal of Gastroenterology 2021;116(1):17-44.

Insomnia in older adults

Insomnia is a common problem among older persons and assessment and treatment can be challenging. cognitive-behavioural therapy for insomnia (CBT-I) is effective, with benefits persisting for 6 months or more. Benzodiazepines have been associated with adverse consequences, including an increased risk of falls, motor vehicle crashes, residual daytime sedation, anterograde amnesia, substance use disorder, and rebound insomnia.

Canadian Family Physician 2021;67(1):25-26.

Topical management of tinea pedis

Tinea pedis is successfully treated with topical antifungals. Terbinafine cream, twice a day for 7 days, is a reasonable prescription option with a short treatment duration and well supported efficacy. Over-the-counter options, such as clotrimazole or miconazole, tend to require a longer treatment duration. Tea tree oil is likely ineffective.

Canadian Family Physician 2021;67(1):30.

Alcohol consumption and risk of cardiovascular outcomes and bleeding in patients with established atrial fibrillation

Data from 2 prospective cohort studies that followed 3852 patients with AF for a median of 3 years shows no significant association between low to moderate alcohol intake and risk of stroke or other cardiovascular events. There was also no significant association between alcohol consumption and bleeding.

CMAJ 2021;193(4):E117-E123.

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