Debbie Rigby rounds up the latest in research news
A systematic search for articles reporting direct observation of inhaler technique has concluded that incorrect inhaler technique is unacceptably frequent and has not improved over the past 40 years. The most frequent MDI errors were in coordination, speed and/or depth of inspiration, and no post-inhalation breath-hold; whilst incorrect preparation, no full expiration before inhalation, and no post-inhalation breath-hold were the most frequent DPI errors.
Medication reconciliation is a part of the medication management process and facilitates improved patient safety during care transitions. This systematic review evaluated the prevalence, types, causes and contributory factors of medication discrepancy. The Australian authors recommended development of a well-designed taxonomy for medication discrepancies and standardized process for conducting and evaluating the practice of medication reconciliation.
Br J Clin Pharmacol 2016;82:645-58.
A systematic review and meta-analysis conducted by Amy Page et al suggests that deprescribing needs to be considered for older people as a routine component of the ongoing medication review process. The authors conclude that patient-specific deprescribing interventions to reduce polypharmacy may improve longevity.
Br J Clin Pharmacol 2016;82:583-623.
The findings of this meta-analysis support an increased risk of MI in antipsychotic drug users. The he odds for developing MI were 88% higher in patients taking antipsychotics compared with individuals who had not taken antipsychotics.
Br J Clin Pharmacol 2016;82:624-32.