Research Roundup

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Debbie Rigby takes a look at the latest in research news

Cannabidiol as a Treatment for Chronic Pain

In a US-based survey of 253 adults, most participants expressed a positive attitude about CBD products as a treatment option, reported positive outcomes when used for multiple different conditions, and would prefer to obtain information about and prescription for CBD from their physicians. They reported believing that CBD was a good treatment option (71.1%), not harmful (74.9%), and not addictive (65.3%).

Journal of Pain Research 2021:14 1241–1250.


Factors Associated with Pain Resolution in those with Knee Pain: The MOST Study

In the MOST cohort study of 1304 patients with knee osteoarthritis, lower BMI, greater quadriceps strength and gardening and moderately intensive recreational activities increased the odds of pain resolution. Walking decreased the odds of pain resolution.

Osteoarthritis Cartilage 2021 Apr 23;S1063-4584(21)00698-1.


Sodium‐glucose co‐transporter‐2 inhibitors and all‐cause mortality

A meta‐analysis of randomized controlled trials has shown that SGLT2 inhibitors reduce all‐cause mortality in randomized controlled trials with a duration of treatment longer than 52 weeks. Treatment with SGLT2 inhibitors was associated with a significant 14% reduction in all‐cause mortality.

Diabetes, Obesity and Metabolism 2021;23(4):1052-6.


Atrial fibrillation and oral anticoagulation in older adults

This editorial on the use of oral anticoagulants in older people with atrial fibrillation suggests that OAC should not be withheld solely because of a person’s age or their risk of falls and that there are significant benefits of OAC in terms of reducing the risk of stroke and mortality. A holistic person-centred approach is recommended to guide shared decision-making on OAC use.

Age and Ageing 2021;50(3):687-9.

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