The latest in research news from Debbie Rigby
In this small (n=103) randomised trial, the DASH diet lowered serum uric acid, and this effect was greater among participants with hyperuricemia. In addition, increased levels of sodium intake reduced serum uric acid, and this effect was greater among participants with high blood pressure at baseline. The DASH diet emphasizes whole grains, fruits, vegetables, and low-fat dairy products with a low intake of red meats, sweets, and saturated fats.
Arthritis & Rheumatology 2016.
This is a great one page summary on the SPRINT trial results. The trial results support systolic BP (SBP) targets <140mm Hg, with SPRINT also suggesting a SBP target of 120mm Hg for those with a 10-year risk of cardiovascular disease ≥20%. In SPRINT, diastolic BP was kept above 65 mm Hg and standing SBP was 110 mm Hg or greater. Lower targets do not apply to patients with diabetes.
Canadian Family Physician 2016;62:638.
Among patients aged 75 years or younger with type 2 diabetes and no previous cardiovascular disease lower blood pressure (110-119 mm Hg) is associated with a significantly lower risk of non-fatal acute myocardial infarction, total acute myocardial infarction, non-fatal cardiovascular disease, total cardiovascular disease and non-fatal coronary heart disease, compared with the reference group (130-139 mm Hg).
IBS is one of the most commonly diagnosed gastrointestinal disorders, and it has a significant impact on quality of life. A low-FODMAP diet has been found to improve symptoms in up to 70% of patients with IBS. Probiotics containing the strain Lactobacillus rhamnosus GG have a beneficial effect in IBS and can be taken concurrently with the diet.
Cleveland Clinic Journal Of Medicine 2016;83(9):655-62.