Research roundup

Debbie Rigby rounds up the latest in research news

The association between insomnia symptoms and risk of cardio-cerebral vascular events

A meta-analysis of prospective cohort studies has demonstrated an association between that insomnia symptoms of difficulty initiating sleep, difficulty maintaining sleep and non-restorative sleep with an increased risk of future cardio-cerebral vascular events. Fifteen studies (23 cohorts) were included showing a 27% increased relative risk of cardio-cerebral vascular events, especially in women.

European Journal of Preventive Cardiology, First Published March 30, 2017.


Managing the drug treatment of rheumatoid arthritis

Rheumatoid arthritis is an inflammatory condition affecting synovial joints. Without treatment, the underlying inflammatory process leads to joint destruction, pain, deformity, disability and accelerated cardiovascular disease. Disease-modifying antirheumatic drugs will attenuate the inflammation. Their benefits are seen at all stages of the disease, however the best outcomes are achieved when they are used shortly after the onset.

Aust Prescr 2017;40:51-8.


Managing hepatitis C in general practice

All oral, direct-acting antiviral treatments for chronic hepatitis C are highly effective and well tolerated. Approximately 95% of patients will be cured with a short course of treatment. All regimens can potentially interact with concomitant drugs and it is essential a comprehensive medication review is conducted with patients prescribed antiviral treatments.

Aust Prescr 2017;40:64-9.


Drug-related problems in patients with erectile dysfunctions and multiple comorbidities

A study of 200 patients with erectile dysfunction and multiple comorbidities has explored the rate, type and risk factors for drug-related problems. There was a significant higher risk of DRPs in patients with benign prostatic hyperplasia, lower urinary tract infection and elderly and end-stage renal disease. Drug interac­tion contributed the most to DRPs occurrence.

Therapeutics and Clinical Risk Management 2017:13 407–419.

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