Research Roundup

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Debbie Rigby examines the latest in research news 

Management of hypertension in an Australian community pharmacy setting – patients’ beliefs and perspectives

This article reports on a small qualitative study trialled in Sydney on pharmacist-led hypertension management. Patients’ (n=18) experiences of the service were extremely positive, especially around pharmacists’ monitoring of blood pressure and provision of advice about medication adherence. Good rapport with the pharmacist and a long-term relationship underpin patient engagement in such services.

International Journal of Pharmacy Practice 2017;25:263-73.


Penicillin Allergy Is Not Necessarily Forever

Most patients who have a history of penicillin allergy are not really allergic to penicillin. Less than 10% of people with penicillin-allergy histories are found to be truly allergic to penicillin. Patients may have had a documented acute penicillin reaction caused by allergic (IgE) antibodies, but those antibodies decline and can disappear with time, resulting in most patients becoming skin-test negative after a decade.

JAMA. 2017;318(1):82-83.


Do oral decongestants have a clinically significant effect on BP in patients with hypertension?

Pseudoephedrine causes an average increase of 1.2 mm Hg in systolic blood pressure (BP) in patients with controlled hypertension. Slight changes in diastolic BP and heart rate were not clinically significant. This article highlights the paucity of literature on treating older patients and those with uncontrolled or secondary causes of hypertension, cerebrovascular disease and coronary artery disease.

J Fam Pract. 2017 June;66(6):E1-E2.


Serum 25-hydroxyvitamin D level, chronic diseases and all-cause mortality

A population-based prospective cohort study conducted in Norway has shown an association between low serum 25(OH)D levels and 30% increased risk of all-cause mortality. The association was not notably influenced by existing chronic diseases including cardiovascular disease, diabetes and cancer.

BMJ Open 2017;7:e017256.



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