Research Roundup

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Debbie Rigby takes a look at the latest in research news 

Development of a clinical pharmacy model within an Australian home nursing service

This paper describes a collaborative, person-centred model of clinical pharmacy support for community nurses and their medication management clients. Pharmacist roles included direct client care and indirect care. Direct care included home visits, medication reconciliation, medication review, medication regimen simplification, preparation of medication lists for clients and nurses, liaison and information sharing with prescribers and pharmacies and patient/carer education. Indirect care included providing medicines information and education for nurses and assisting with review and implementation of organisational medication policies and procedures.

BMJ Open 2017;7:e018722.


Osteosarcopenia: A new geriatric syndrome

Osteoporosis and sarcopenia are often interrelated and comprise a syndrome called osteosarcopenia. Patients with osteosarcopenia represent an important subset of frail individuals at higher risk of institutionalisation, falls and fractures. A healthy lifestyle and regular exercise (ie strength, balance) are the first-line prevention and treatment choices for osteosarcopenia; however, pharmacological treatment for osteoporosis, and vitamin D and calcium supplementation may be required.

Australian Family Physician 2017;46(11):849-53.


Drug-Induced Vitamin B12 Deficiency: A Focus on Proton Pump Inhibitors and Histamine-2 Antagonists

Proton pump inhibitors have been associated with an increased risk of vitamin B12 deficiency. This review of primary literature found conflicting evidence of increased risk of developing vitamin B12 deficiency in patients who are exposed to extended durations of therapy with PPIs. No evidence was found to support the extended use of H2RA monotherapy causing vitamin B12 deficiency.

Journal of Pharmacy Practice 2017;30(6).


A practical approach to the management of nocturia

Nocturia is defined as the need to void ≥1 time during the sleeping period of the night. Clinically relevant nocturia (≥2 voids per night) affects 2%-18% of those aged 20-40 years, rising to 28%-62% for those aged 70-80 years. Low-dose, gender-specific desmopressin has proven effective in nocturia due to idiopathic nocturnal polyuria. The timing of diuretics is an important consideration, and they should be taken mid-late afternoon, dependent on the specific serum half-life.

International Journal of Clinical Practice 2017;71(11):e13027.



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