What is the place of proton pump inhibitors in reflux management?

Proton pump inhibitors (PPIs) have become a mainstay in the treatment of gastro-oesophageal reflux disease (GORD) because of their impressive efficacy.1 The key to ensuring the best outcomes for patients is ensuring that recommendations for PPI use reflect the latest evidence and clinical guidelines. PPIs for the management of frequent reflux2 PPIs reduce acid secretion

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