Debbie Rigby takes a look at the latest in research news
Chronic obstructive pulmonary disease (COPD) is a highly debilitating disease that represents a substantial and growing health burden in women. There is increasing evidence for gender-related differences in COPD risk, progression and outcomes. However, the disease receives scant attention as a women’s health issue. This review article highlights suggestions for achieving better outcomes for women.
Chest, Available online 2 November 2016
Cranberry has been recommended to prevent recurrent urinary tract infections. However a randomised control trial of 185 older people (mean age 86.4 years) has shown cranberry capsules have no significant difference in presence of bacteriuria plus pyuria over 1 year compared to placebo. Two oral cranberry capsules, each capsule containing 36mg of the active ingredient proanthocyanidin (20 ounces of cranberry juice) administered once a day.
A randomised controlled trial of 24,081 patients has concluded that moderate doses of celecoxib (200mg daily) are non-inferior to ibuprofen or naproxen with regard to cardiovascular safety. The risk of gastrointestinal events was significantly lower with celecoxib than with naproxen or ibuprofen; and the risk of renal events was significantly lower with celecoxib than with ibuprofen but was not significantly lower with celecoxib than with naproxen.
New Engl J Med, November 13, 2016.
The effectiveness and safety of statins have been documented by numerous RCTs; however concerns about possible statin-associated adverse effects impact negatively on patient adherence. This article discusses the true incidence and management of statin-associated muscle symptoms.