Research Roundup

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Debbie Rigby rounds up the latest in research news 

The impact of a pharmacist on post-take ward round prescribing and medication appropriateness

Clinical pharmacist participation on a post-admission ward round leads to improved medication-related communication and improved medication appropriateness using the START/STOPP checklists but did not significantly improve health care outcomes. The mean change in medication appropriateness was equivalent to deprescribing 13 potentially inappropriate medications and equivalent to 13 extra appropriate medications per 100 patients. Length of stay and 28-day mortality were unchanged.

International Journal of Clinical Pharmacy 2019;41(1):65-73.


No level of alcohol consumption improves health

A systematic analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 for 195 countries and territories, 1990–2016 shows there is no safe level of alcohol consumption. Among those aged 15–49 years was the leading risk factor globally in 2016, with 3·8% of female deaths and 12·2% of male deaths attributable to alcohol use.

Lancet 2019;392:987-8.


Impact of non-drug therapies on asthma control

A systematic review of 82 publications concludes that most measures attempting to reduce exposure to dust mites and dietary interventions were ineffective. Renovating homes to reduce exposure to allergens and indoor pollutants improved control. Patient education programmes significantly improved asthma control. These results call for a stronger emphasis on patient-focused care in asthma, in particular on their information needs and self-management skills.

European Journal of General Practice, 2019


Association of Tramadol With All-Cause Mortality Among Patients With Osteoarthritis

In this cohort study that included 88 902 patients aged 50 years and older with osteoarthritis, initial prescription of tramadol was associated with a significantly increased risk of mortality over 1 year compared with initial prescription of naproxen (hazard ratio [HR], 1.71), diclofenac (HR, 1.88), celecoxib (HR, 1.70), and etoricoxib (HR, 2.04), but not compared with codeine (HR, 0.94).

JAMA. 2019;321(10):969-982.



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