An “alarming” number of children under five are being prescribed asthma medication outside of national guidelines, according to new research presented in Adelaide
The study is being shared with health professionals at the Australia and New Zealand Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science (TSANZRS 2018).
“This finding identifies an area of great concern to our community,” said Professor Allan Glanville, President of the Thoracic Society of Australia and New Zealand (TSANZ), which is hosting the conference.
“Correct asthma management in children – particularly in those under five years – is absolutely critical to prevent exacerbations, increase the chance of prolonged remission of asthma and build healthy lungs into adult life.
“We have always known that adherence to medications in this group has been a challenge. Finding evidence that medications are being prescribed incorrectly from the outset highlights the importance of health care provider education as well as the need to increase public awareness,” he said.
More than half of the approximately 40,000 asthma hospitalisations in Australia each year are in children aged 0-14, peaking in children aged 0-4 years. Excessive use of health care resources is a marker of poorly controlled asthma and is associated with inadequate or inappropriate use of asthma medication.
The Australian Asthma Handbook by the National Asthma Council Australia suggests a stepwise approach to the management of asthma with stepping up or down asthma medications depending on the control of asthma symptoms. The guideline advises that inhaled fixed dose combination (FDC) medication (combination of inhaled steroids and a long acting beta agonist) are not recommended in children aged under five. If the initial use of low-dose inhaled corticosteroid alone fails to control the symptoms, other treatment options are preferable.
The new study, conducted by researchers based at UNSW Sydney and Sydney Children’s Hospital, found that an estimated 800,000 children are prescribed an asthma medication each year across the country.
The prescription of fixed dose combination inhalers (LABA/ICS) is common in children under five years of age, despite this being outside of the age recommended in national guidelines.
There is also high prescribing of these inhalers without prior prescribing of inhaled corticosteroids (ICS)—also not compliant with guidelines.
“There is clearly a need for creating awareness among health care providers about asthma management guidelines,” said lead researcher, Dr Nusrat Homaira from the UNSW School of Women’s and Children’s Health.
The researchers say the finding is a concern against a background of asthma deaths that, after years of being stable, are slowly increasing, and numerous studies highlighting poor asthma control across the country.
Earlier research has found that only 25% of adults and 40% of children with asthma have a written asthma plan. In addition, nearly 40% of people with asthma use relievers rather than preventive, anti-inflammatory medications to avoid exacerbations in the first place.
“The Australian Asthma Handbook advises doctors treating children under five with asthma to use the lowest level of medication required to minimise the side effects, so that they can live well with asthma, and to use a stepped approach to adjusting their asthma medication,” said Professor Amanda Barnard, General Practitioner and Chair of National Asthma Council Australia’s Guidelines Committee.
“Doctors should check whether the symptoms are due to asthma, incorrect inhaler technique, or poor adherence before considering stepping up medication.”
Michele Goldman, CEO of Asthma Australia, said GPs need to be aware of the guidelines and ensure they are prescribing medication in line with them.
“Open communication between GPs, parents and people with asthma is also very important, so that concerns can be discussed.
“Education is vital for a person with asthma to understand why they need their medication, how it works and the correct way to use their delivery device, such as a puffer with a spacer.
“This will help improve adherence and ensure that patients are getting the most benefit from their medication. This approach is most likely to limit asthma symptoms and flare-ups, and reduce the likelihood of higher doses or stronger medication being prescribed unnecessarily.”