Debbie Rigby rounds up the latest in research news
A Cochrane systematic review of 79 RCTs (n=112,059) of 12 to 72 months duration has concluded that increasing EPA and DHA has little or no effect on mortality or cardiovascular health. Low-quality evidence suggests ALA may slightly reduce CVD event risk, CHD mortality and arrhythmia, but makes little or no difference to all-cause or cardiovascular deaths or coronary events.
Cochrane Database of Systematic Reviews 2018, Issue 7.
A pharmacist-led medication review was not effective at reducing the anticholinergic/sedative load, as measured by the Drug Burden Index (DBI) in this randomised controlled single blind trial, conducted through 15 community pharmacies in Netherlands. Patients included in the trial were aged ≥65 years (mean age 75.7 years) who used ≥5 medicines for ≥3 months, including at least one psycholeptic/psychoanaleptic medication. The authors highlighted that 3-month follow-up might have been too short to detect full effects of medication review.
BMJ Open 2018;8:e019042.
A systematic literature review has concluded Community pharmacies are well suited to deliver a wide range of point-of-care tests. Point-of-care tests in 11 studies included blood glucose, cholesterol, creatinine, uric acid, liver enzymes, international normalized ratio for anticoagulation therapy, bone mineral density for osteoporosis, forced expiratory volume for chronic obstructive pulmonary disease, and infection with human immunodeficiency virus. Interventions applying these tests were effective overall.
Research in Social and Administrative Pharmacy, available online 20 July 2018.
A systematic review of 22 studies has concluded that community pharmacist‐led interventions have been shown to improve patients’ adherence and contribute to better blood pressure control, cholesterol management, chronic obstructive pulmonary disease and asthma control. Studies in this review, however, did not report statistically significant effects of interventions on diabetes or depression control.
International Journal of Pharmacy Practice, first published 21 June 2018.